|Frost Awarded $600,000 Susan G. Komen for the Cure Grant|
July 13, 2011
UAB researcher Andra Frost, M.D., associate professor in the Department of Pathology and scientist in the Experimental Therapeutics Program of the UAB Comprehensive Cancer Center, has been awarded a Susan G. Komen for the Cure research grant for $600,000 to study the role of the oncogene Gli1 in the metastasis of triple negative breast cancer, an especially aggressive subtype of the disease.
Frost is hoping to understand how Gli1 is promoting the metastasis of triple negative breast cancer. Currently there are no widely used targeted therapies for the treatment of triple negative breast cancer. Ultimately, Frost says, “We want to show that inhibiting the function of the Gli1 will slow or stop the growth and metastasis of triple negative breast cancer.”
The UAB Comprehensive Cancer Center is among the 40 cancer centers in the nation to meet the stringent criteria for the National Cancer Institute's comprehensive designation. The center is a leader in groundbreaking research, reducing cancer disparities and leading-edge patient care.