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Shared Facilities
Biostatistics and Bioinformatics - Alan Cantor , Ph.D., Director
The primary objective of the Biostatistics and Bioinformatics Shared Facility (BBSF) is to serve as a focal point from which the UAB Comprehensive Cancer Center's investigators may draw statistical and bioinformatics expertise for planning, management and analysis of their studies.
Contact: (205) 996-6122; http://www.uab.edu/ccc/biostatistics
Clinical Protocol and Data Management - Andres Forero, M.D., Director
The Clinical Protocol and Data Management Shared (CPDM) Facility provides central management for the implementation, coordination, and conduct of clinical trials developed by the Cancer Center faculty and by extramural collaborators associated with SPOREs, other cancer centers, the National Cancer Institute, industry and cooperative groups.
Contact: (205) 934-0309
Community Recruitment and Retention - Mona Fouad, M.D., MPH, Director
The Community Recruitment and Retention (CRR) Shared Facility is an infrastructure designed to facilitate and assist Cancer Center investigators in recruiting subjects to participate in clinical research and to provide linkage between the community and UAB Researchers. The CRR is particularly focused on efforts to refine recruitment strategies, particularly for population-based studies, among minority participation in clinical trials.
Contact: (205) 934-4307
DNA Sequencing - Beatrice Hahn, M.D., Director
The DNA Sequencing Core has been in operation for 15 years, generating more than 34 million base pairs of primary sequence in the past five years and serving more than 300 individual users. It allows Cancer Center members access to a facility that provides DNA sequence analysis in a cost-effective, timely manner.
Contact: (205) 934-0412
Gene Expression - Michael Crowley, Ph.D., Director
The Gene Expression facility provides support to Cancer Center investigators interested in microarray technology. The facility was established using Cancer Center developmental funds and is focused primarily on the study of gene expression analyses as they relate to human malignancy.
Contact: (205) 975-2012
High Resolution Imaging - Kent Kyser, Ph.D., Director
This core facility offers access to high resolution imaging facilities for members of the Cancer Center. The facility contains state-of-the-art Multiphoton Laser Scanning Microscopy, Confocal Laser Scanning Microscopy and digital microscopy equipment configured with deconvolution software and is staffed by experienced technical specialists.
Contact: (205) 975-7225
Mass Spectroscopy - Stephen Barnes, Ph.D., and Helen Kim, Ph.D., Directors
The Mass Spectrometry Shared Facility is organized to provide a variety of analytical and technical services using mass spectrometry to UAB Comprehensive Cancer Center investigators.
Contact: (205) 934-7117; http://www.uab.edu/proteomics
Molecular Biology - Casey Morrow, Ph.D., Director
The Molecular Biology Core (MBC) is a joint facility between the Cancer Center and Center for AIDS Research (CFAR). The purpose of the MBC has been to provide the opportunity for investigators to rapidly bridge the gap between cloning of genes and structure function studies. The Core provides expertise in cloning, PCR, site-directed DNA mutagenesis and production of recombinant proteins. These are all critical elements toward understanding the complex biology and structure of high-priority proteins relevant to cancer research.
Contact: (205) 934-5705
Molecular NMR - Rama Krishna, Ph.D., Director
The Molecular NMR Shared Facility was one of the original shared facilities established by the Comprehensive Cancer Center to provide high-quality sample analysis to the Center’s faculty membership. The primary objectives of the facility are to provide “state-of-the-art” instrumentation for use by the Center members in their individual research programs and research related to the Center’s Core Programs.
Contact: (205) 934-5695
Proteomics Research Facility - James A. Mobley, Ph.D., Director
The Proteomics Research Facility is based securely on a strong informatics platform, which is fed by the latest tools in mass spectrometry, proteomics, small molecule discovery, and clinical databases, allowing for a more in depth systems biology based overview of each disease that we study. The primary bases for this research is to identify clinically significant and non-invasive biomarkers for early detection of disease and also to identify novel therapeutics for the treatment of disease.
Contact: (205) 996-6363; http://www.urology.uab.edu/urologyresearch/
Small Animal Imaging - Kurt Zinn, D.V.M., M.S., Ph.D., Director
The Small Animal Imaging Facility supports molecular imaging applications for cancer, including early detection of cancer and therapy evaluation. The facility provides detailed imaging evaluation of new cancer treatments, and thereby accelerates their translation to human trials.
Contact: (205) 975-6414
Tissue Procurement - William Grizzle, M.D., Ph.D., Director
The Tissue Procurement Facility provides investigators with access to adequate numbers of high quality human tumor and control tissues with associated histopathologic and demographic data.
Contact: (205) 934-4214
Transgenic Animal/Embryonic Stem Cell - Bob Kesterson, Ph.D., Director
With completion of the human and mouse genome sequences, genetically modified mouse models are more essential than ever in elucidating disease mechanisms and developing approaches to therapies for cancer. The Transgenic Animal Facility provides unique services for the development of genetically modified mouse models and has a long track record of outstanding service.
Contact: (205) 934-7206
X-Ray Crystallography - Lawrence DeLucas, OD, Ph.D, D.Sc. (Hon.), Director
The X-ray Crystallography Shared Facility provides a unique, state-of-the-art crystallography facility for Cancer Center members and other regional scientists. In the last five years, the facility has acquired extensive high-throughput capabilities, including dedicated access to two beamlines at the Argonne Synchrotron Facility, a fully-automated nano-crystallization laboratory and a liquid diffusion crystallization via an automated microfluidics system.
Contact: (205) 934-5329
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