Unless otherwise noted, all questions regarding these or any other funding opportunities should be directed to Susan Ruppert, (205) 975-0359 or firstname.lastname@example.org.
Translational Research Initiative Awards
The UAB Comprehensive Cancer Center, in conjunction with the UAB NCTN LAPS program, invite innovative research proposals focused on translational investigations of pathways, potential drug targets and biomarkers in human tumor samples. The intent of this RFA is to promote new collaborations between basic and clinical investigators, based on the analysis of human biological samples obtained from patients, in support of novel translational research programs in drug discovery, clinically relevant pathway interactions, or biomarkers of therapeutic response.
Awards (5-10) in the amount of $10- 20K each will be made available to support the molecular analysis of patient-derived samples (such as immunohistochemical staining, or proteomic/genomic analyses), obtained through banked tumor samples and/or associated with clinical trials. Preference will be given to collaborations between basic and translational/clinical faculty.
APPLICATION INFORMATION: The following should be submitted in a single pdf file to Dr. Susan Ruppert, email@example.com, by 5 p.m. on October 7, 2016.
Questions regarding budget or assistance with identifying potential collaborators and/or sources of patient samples should be directed to Dr. Michael Bertram, firstname.lastname@example.org.
• A 1-2 page description of the project, including the rationale for the proposed studies, a description of the patient materials, a description of the collaborating faculty, and the study objectives. If applicable, a description of an associated clinical trial can be included as an appendix.
• Biosketch (NIH format) of collaborating basic and translational/clinical PIs.
• A brief description of the requested funds. Allowable expenses include reagents, core facility fees (for Ex. RNA-seq, DNA nanostring, laser capture), and supplies. Costs not allowed include: salary support, travel, or equipment.
• Applications are simply extensions of previous or ongoing, extramurally federally funded research will not be considered.
• Awardees will be notified by November 1, 2016.
New Pilot Program for Collaborative Research
The UAB Comprehensive Cancer Center (CCC) and the UAB Center for AIDS Research (CFAR) are pleased to announce a new pilot program to fund collaborative research projects in the area of Non-AIDS Defining Cancers (NADCs) in aging individuals with HIV.
Topics include, but are not limited to:
Clinical outcomes research- links between NADC and anti-retroviral therapy (ART) regimens, efficacy of cancer therapies in aging HIV population
Role of obesity/energetics, microbiome in NADC incidence and outcomes
Co-infection with HPV or Hepatitis B – basic biology, role in cancer incidence, progression, detection and prevention in aging HIV population
Immunology and inflammation- role of ART in immunologic response in NADC development, role of PD-L1-mediated immunosuppression in cancer progression in HIV-infected individuals.
Awardees may request access to tissue samples and medical records from CNICS (www.uab.edu/cnics/).
TWO-STAGE APPLICATION PROCESS
LETTER OF INTENT (LOI) due on September 15, 2016
LOIs should include a project description including relevance, hypotheses and Specific Aims (2 pages).
Please email LOIs to Susan Ruppert.
A review panel will select applications to go forward to a full proposal.
FULL PROPOSAL due on October 31, 2016
If requested to submit, the full proposal should include significance, preliminary data (helpful if available, but not required), innovation and approach (6 pages). A detailed budget for $100,000 is also required. Forms and instructions will be provided with the invitation to submit a full application.
CONTACT for answers to questions, help in identifying collaborators and to submit applications please email Susan Ruppert (email@example.com)